In this blog, I would like to talk about the perspective of the relationship between immunity and gut bacteria.
In my previous blog (dated 4 November), I mentioned that in order to maintain normal intestinal flora and health, it is necessary to increase good bacteria and that one of the most effective ways to do this is to take dietary fibre and oligosaccharides as prebiotics to feed the good bacteria, and burdocks have both ingredients. Burdock has both ingredients.
It is well known that the immune system attacks and eliminates foreign substances such as bacteria and viruses that enter the body from the outside, as well as abnormal cells such as cancer cells that develop in the body, in order to protect the body from disease. Maintaining a healthy intestinal flora is also linked to maintaining a proper immune system.
Immunity is divided into innate immunity and acquired immunity, and it is believed that increasing good bacteria (e.g. lactic acid bacteria, mainly bifidobacteria) mainly contributes to activating innate immunity.
On the other hand, it is now known that not only good bacteria, but also Commensal bacteria (0mnivorous bacteria) are required for acquired immunity.
In November 2013, a research group from RIKEN, the University of Tokyo, the Institute for Advanced Biosciences at Keio University and others published a research report entitled ‘Fatty acid produced by gut bacteria boosts the immune system’. has been published.
The following information was included in this report.
Their research demonstrates that butyric acid, a short-chain fatty acid produced by commensal bacteria acts on naïve T cells to promote their differentiation into Treg cells. It achieves this through epigenetic changes that regulate the expression of the genes responsible for differentiation of naïve T cells into Treg cells.
Recent research has shown that Treg cells have the ability to suppress immune responses, and that they play a role in suppressing excessive immune responses that can cause autoimmune diseases, inflammatory diseases, and allergic diseases.
Treg cells (regulatory T cells) are immune cells that negatively regulate the immune system and work to maintain immune system homeostasis in order to prevent such autoimmune diseases and accidental destruction of healthy cells. This has led to the development of new therapeutic approaches to cancer.
The mechanism for producing Treg cells is important for maintaining our normal health, and the butyric acid-producing bacteria that produce the butyric acid needed to activate them are indispensable. So, what feeds these butyric acid-producing bacteria? It is fructooligosaccharides.
Japanese people have eaten burdock root as an energizing vegetable for about 400 years. The evidence for this has finally been discovered in modern times. The dietary fiber and fructooligosaccharides (inulin) in burdock contribute to maintaining normal intestinal flora, strengthening the immune system and protecting against viruses and bacteria. It did more than just improve bowel movements.
I have introduced the benefits of burdock over the course of two parts, Prt1 and Part2. I would like to take this opportunity to invite you to try burdock powder, which you can easily try to see the benefits of burdock. It is especially recommended for allergy symptoms such as hay fever.
Burdock powder that improves intestinal flora and boosts immunity and – mura network